EVALUATION OF HAEMATOLOGICAL PARAMETER OF ANAEMIC RAT RECEIVING IRON RICE DIET
Abstract
Anemia, including iron deficiency anemia; is one of the most common cause of anemia cause by few unhealthy red blood cells present in blood or by lack of iron in blood and emerges as a major public health problem in Cameroon.
Moreover, since it’s a nutritional disorder, supplements have been formulated to reduce iron deficiency anemia, and leading to the bioavailability of iron for synthesis of hemoglobin in higher concentration in blood.
But dietary like; tofu, oats, dried fruits, nuts, legumes (baked, chickpeas,) sweet potatoes, have positive effects on iron deficient anemia, with snails being one of its rich source, due to the present of its own iron called Chrysomallon squamiferum(seapangolin), and it rich in, calcium, selenium and omega-3 fatty acids contains, the present study investigate the effects of pre-treatment with snail supplements.
The study was conducted on 36 Wistar rats, were gotten from the animal house and transported to the school lab and were the acclimatised before any work was done on them, were divided into six groups of 6 rats each, and pre-treated was as follows.
The normal control (NO) received distilled water, negative control (NC), was only induced with iron deficient anemia , test groups 1 and 2, received cooked powdered snails supplement at doses of 150and 250mgFe/kg, test groups 3 , received raw snail supplements at doses 250mgFe/kg, and the positive control (PC) received propranolol (standard drug) 1 day before sacrifice.
Iron deficient anemia was induced by intra peritoneal injection of iron sulphate (FeSO4 40 mg/kg) for 2 consecutive days before sacrifice. Eventually, the animals were sacrificed on day 13, after an overnight fast and blood samples collected for hematological parameter evaluation. Based on the results, FeSO4 administration significantly decreased hematological parameters compared to the normal control group.
Additionally, pre-treatment showed significant restoration of hematological parameters, including WBC count and its subtypes compared to the, FeSO4 group. pre-treatment with cooked snails decreases hematological parameters compared to the standard drug, with raw snails showing a better effect.
Check out: Biochemistry Project Topics with Materials
| Project Details | |
| Department | Biochemistry |
| Project ID | BCH0022 |
| Price | Cameroonian: 5000 Frs |
| International: $15 | |
| No of pages | 50 |
| Methodology | Experimental |
| Reference | Yes |
| Format | MS word & PDF |
| Chapters | 1-4 |
| Extra Content | table of content, |
This is a premium project material, to get the complete research project make payment of 5,000FRS (for Cameroonian base clients) and $15 for international base clients. See details on payment page
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EVALUATION OF HAEMATOLOGICAL PARAMETER OF ANAEMIC RAT RECEIVING IRON RICE DIET
| Project Details | |
| Department | Biochemistry |
| Project ID | BCH0022 |
| Price | Cameroonian: 5000 Frs |
| International: $15 | |
| No of pages | 50 |
| Methodology | Experimental |
| Reference | yes |
| Format | MS word & PDF |
| Chapters | 1-4 |
| Extra Content | table of content, |
Abstract
Anemia, including iron deficiency anemia; is one of the most common cause of anemia cause by few unhealthy red blood cells present in blood or by lack of iron in blood and emerges as a major public health problem in Cameroon.
Moreover, since it’s a nutritional disorder, supplements have been formulated to reduce iron deficiency anemia, and leading to the bioavailability of iron for synthesis of hemoglobin in higher concentration in blood.
But dietary like; tofu, oats, dried fruits, nuts, legumes (baked, chickpeas,) sweet potatoes, have positive effects on iron deficient anemia, with snails being one of its rich source, due to the present of its own iron called Chrysomallon squamiferum(seapangolin), and it rich in, calcium, selenium and omega-3 fatty acids contains, the present study investigate the effects of pre-treatment with snail supplements.
The study was conducted on 36 Wistar rats, were gotten from the animal house and transported to the school lab and were the acclimatised before any work was done on them, were divided into six groups of 6 rats each, and pre-treated was as follows.
The normal control (NO) received distilled water, negative control (NC), was only induced with iron deficient anemia , test groups 1 and 2, received cooked powdered snails supplement at doses of 150and 250mgFe/kg, test groups 3 , received raw snail supplements at doses 250mgFe/kg, and the positive control (PC) received propranolol (standard drug) 1 day before sacrifice.
Iron deficient anemia was induced by intra peritoneal injection of iron sulphate (FeSO4 40 mg/kg) for 2 consecutive days before sacrifice. Eventually, the animals were sacrificed on day 13, after an overnight fast and blood samples collected for hematological parameter evaluation. Based on the results, FeSO4 administration significantly decreased hematological parameters compared to the normal control group.
Additionally, pre-treatment showed significant restoration of hematological parameters, including WBC count and its subtypes compared to the, FeSO4 group. pre-treatment with cooked snails decreases hematological parameters compared to the standard drug, with raw snails showing a better effect.
Check out: Biochemistry Project Topics with Materials
This is a premium project material, to get the complete research project make payment of 5,000FRS (for Cameroonian base clients) and $15 for international base clients. See details on payment page
NB: It’s advisable to contact us before making any form of payment
Our Fair use policy
Using our service is LEGAL and IS NOT prohibited by any university/college policies. For more details click here
We’ve been providing support to students, helping them make the most out of their academics, since 2014. The custom academic work that we provide is a powerful tool that will facilitate and boost your coursework, grades and examination results. Professionalism is at the core of our dealings with clients.
For more project materials and info!
Contact us here
OR
Click on the WhatsApp Button at the bottom left
Email: info@project-house.net
