RELATIONSHIP BETWEEN INFLAMMATION AND VITAMIN D DEFICIENCY IN DIABETIC PATIENTS AT BUEA REGIONAL HOSPITAL
Abstract
Background: There is a growing increase in the prevalence of vitamin D deficiency worldwide and is seen to be associated with a number of chronic diseases one of which includes diabetes. The link between vitamin D deficiency and diabetes became clearer after the discovery of vitamin D receptors on pancreatic β-cells, adipose tissues, skeletal muscles and immune cells, indicating vitamin D plays a role in glucose homeostasis.
Objective: To find the association between inflammation and vitamin D deficiency in diabetic patients attending the Buea Regional Hospital
Materials and methods: A hospital based cross-sectional study conducted on 125 study participants with type 2 diabetes mellitus aged 25years and above recruited by convenience sampling method. A volume of 5ml of blood was be collected from eligible participants by venipuncture for analysis of serum vitamin D, fasting plasma glucose, glycated hemoglobin, creatinine and high-sensitivity C-reactive protein levels.
Results: Of the 125 participants recruited, 66.4% had hypovitaminosis D with 28.8% deficient and 37.6% insufficient and a mean serum vitamin D concentration of 28.46±12.96. A significant inverse relationship was seen between vitamin D status and fasting plasma glucose with r=-0.214 and p=0.016. However, there was no significant relationship between vitamin D and glycated hemoglobin levels. A great proportion of participants (81.6%) had inflammation. A significant association was seen between vitamin D status and inflammation with a p<0.001.
Conclusion: Hypovitaminosis D is associated with inflammation and high glucose levels in type 2 diabetic patients. However, no association was seen between serum vitamin D levels and diabetic complications.
Check out: Health Science Project Topics with Materials
Project Details | |
Department | Health Science |
Project ID | HS0065 |
Price | Cameroonian: 5000 Frs |
International: $15 | |
No of pages | 70 |
Methodology | Descriptive |
Reference | yes |
Format | MS word & PDF |
Chapters | 1-5 |
Extra Content | table of content, questionnaire |
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RELATIONSHIP BETWEEN INFLAMMATION AND VITAMIN D DEFICIENCY IN DIABETIC PATIENTS AT BUEA REGIONAL HOSPITAL
Project Details | |
Department | Health Science |
Project ID | HS0065 |
Price | Cameroonian: 5000 Frs |
International: $15 | |
No of pages | 70 |
Methodology | Descriptive |
Reference | yes |
Format | MS word & PDF |
Chapters | 1-5 |
Extra Content | table of content, questionnaire |
Abstract
Background: There is a growing increase in the prevalence of vitamin D deficiency worldwide and is seen to be associated with a number of chronic diseases one of which includes diabetes. The link between vitamin D deficiency and diabetes became clearer after the discovery of vitamin D receptors on pancreatic β-cells, adipose tissues, skeletal muscles and immune cells, indicating vitamin D plays a role in glucose homeostasis.
Objective: To find the association between inflammation and vitamin D deficiency in diabetic patients attending the Buea Regional Hospital
Materials and methods: A hospital based cross-sectional study conducted on 125 study participants with type 2 diabetes mellitus aged 25years and above recruited by convenience sampling method. A volume of 5ml of blood was be collected from eligible participants by venipuncture for analysis of serum vitamin D, fasting plasma glucose, glycated hemoglobin, creatinine and high-sensitivity C-reactive protein levels.
Results: Of the 125 participants recruited, 66.4% had hypovitaminosis D with 28.8% deficient and 37.6% insufficient and a mean serum vitamin D concentration of 28.46±12.96. A significant inverse relationship was seen between vitamin D status and fasting plasma glucose with r=-0.214 and p=0.016. However, there was no significant relationship between vitamin D and glycated hemoglobin levels. A great proportion of participants (81.6%) had inflammation. A significant association was seen between vitamin D status and inflammation with a p<0.001.
Conclusion: Hypovitaminosis D is associated with inflammation and high glucose levels in type 2 diabetic patients. However, no association was seen between serum vitamin D levels and diabetic complications.
Check out: Health Science Project Topics with Materials
This is a premium project material, to get the complete research project make payment of 5,000FRS (for Cameroonian base clients) and $15 for international base clients. See details on payment page
NB: It’s advisable to contact us before making any form of payment
Our Fair use policy
Using our service is LEGAL and IS NOT prohibited by any university/college policies. For more details click here
We’ve been providing support to students, helping them make the most out of their academics, since 2014. The custom academic work that we provide is a powerful tool that will facilitate and boost your coursework, grades and examination results. Professionalism is at the core of our dealings with clients
For more project materials and info!
Contact us here
OR
Click on the WhatsApp Button at the bottom left
Email: info@project-house.net